Dr. Álvarez-Rodríguez
I am a Biologist and PhD (University of León, Spain) with years of research experience in the field of comparative animal reproduction. During my PhD, supervised by Professor de Paz and Professor Anel, I acquainted and experienced in the application of different laboratory techniques and instruments such as flow cytometry, RNA analysis: microarray and bioinformatics, etc for comparative studies of mammalian spermatozoa and the cross-talk with the female genital tract. Member of the board and scientific committee of the Spanish Association for Animal Reproduction (AERA; https://aera.org.es/).
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Honorific Collaborator
University of León, León, Spain
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Docent in Cell and Molecular Biology of Reproduction
University of Linköping, Linköping, Sweden
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Scientific Projects and Grants (2020-2024)
The immunological paradox of pregnancy and embryo mortality in pigs, where does it start? FORMAS (A Swedish Research Council for sustainable development). Role: principal investigator. Status: granted. 3-year-project: 2020-2024.
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Modulation of female genital immune homeostasis by seminal exosomes: a conserved role for fertility? (EXOIMMUNE). JIN. Role: principal investigator. Status: granted. 3-year-project: 2020-2022.
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Modulation of female reproductive tract immune homeostasis by seminal extracellular vesicles. RyC. Role: principal investigator. Status: granted. 5-year-project: 2022/05/01 – 2027/04/30.
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Proyectos Generación Conocimiento 2022 (MECAPSTORAGE). MICINN. Role: principal investigator. Status: granted. 3-year-project: 2023/10/01 – 2026/09/30.
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Consolidación Investigadora 2023 (MECAPCRYO). MICINN. Role: principal investigator. Status: granted. 2-year-project: 2024/04/01 – 2026/03/31.
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Scientific Publications (2024-2025)
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Martín-San Juan A, de Mercado M, Nieto-Cristóbal H, Cabero A, Silvestre MA, Morrell JM, Álvarez-Rodríguez M. Protective effect of supplementation with water soluble β-carotene and α-tocopherol in boar sperm cooling-freezing extender, but not in the thawing extender. Animal Reproduction Science 274 (2025) 107792. https://doi.org/10.1016/j.anireprosci.2025.107792
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Álvarez-Rodríguez M*, García-Calvo L*, Gardela J, Ruiz-Conca M, Olvera-Maneu S, López-Béjar M, Martinez-Pastor F, Vicente-Carrillo A. Effect of semen extraction in the metabolite and hormonal content of rabbit seminal plasma. Veterinary Medicine and Science, 2025; 11:e70236. https://doi.org/10.1002/vms3.70236
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Khan KI, Hazary EH, Miah G, Das A, Momin M, Álvarez-Rodríguez M, Wright D, Rodríguez-Martinez H, Santiago-Moreno J. Effects of STAT5B and BMPR-1B genes on growth and production traits in Red Jungle Fowl, Fayoumi, Hilly chickens, and their crossbreeds. South African Journal of Animal Science 2024, VOL 54. http://dx.doi.org/10.4314/sajas.v54i5.12
Alba E, Castaño C, Toledano-Díaz A, Velázquez R, Martínez-Madrid B, Gómez-Crespo A, Álvarez-Rodríguez M, Rodríguez-Martinez H, Santiago-Moreno J. Detection of androgen receptors in spermatozoa of small ruminants: a putative modulation pathway of cryoresistance through AQP3. Int. J. Mol. Sci. 2024, 25, 11972. https://doi.org/10.3390/ijms252211972
Martín-San Juan A, Gala N, Nieto-Cristóbal, Álvarez-Rodríguez M*, Mercado E,. Effect of the addition of exogenous progesterone and the progesterone receptor inhibitor (RU 486) on boar cryopreservation semen extenders. Research in Veterinary Science. 2024 180, 105400. https://doi.org/10.1016/j.rvsc.2024.105400.​
Álvarez-Rodríguez M, Nieto-Cristóbal H, de Mercado E. Bovine serum albumin (BSA) inclusion in the thawing extender improves boar sperm membrane and acrosomal integrity. Reproduction in Domestic Animals. 2024;59(Suppl. 3):e14592. https://doi.org/10.1111/rda.14592
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Pequeño B, Millán de la Blanca MG, Castaño C, Toledano-Díaz A, Esteso MC, Alba E, Arrebola FA, Ungerfeld R, Martinez-Madrid B, Álvarez-Rodríguez M, Rodríguez-Martínez H, Santiago-Moreno J. Cooling rate modifies the location of aquaporin 3 in spermatozoa of sheep and goat. Theriogenology2024, 223, 29-35. https://doi.org/10.1016/j.theriogenology.2024.04.008
Rodríguez-Martínez H, Martinez C.A., Álvarez-Rodríguez M, Martínez E.A., Roca J. Reproductive physiology of the boar: what defines the potential fertility of an ejaculate? Animal Reproduction Science 2024, 107476. https://doi.org/10.1016/j.anireprosci.2024.107476
Álvarez-Rodríguez M, Tomás-Almenar C, Nieto-Cristóbal H, de Mercado E. Evaluation of Different Thawing Protocols on Iberian Boar Sperm Preserved for 10 Years at Different Liquid Nitrogen Levels. Animals. 2024; 14(6):914. https://doi.org/10.3390/ani14060914
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Lacalle E, Fernández-Alegre E, Gómez-Giménez, Álvarez-Rodríguez M, Martín-Fernández B, Soriano-Úbeda C, Martínez-Pastor F. Application of Flow Cytometry Using Advanced Chromatin Analyses for Assessing Changes in Sperm Structure and DNA Integrity in a Porcine Model. Int. J.Mol. Sci. 2024, 25, 1953. https://doi.org/10.3390/ijms25041953
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Álvarez-Rodríguez M, Martinez CA, Gardela J, Nieto H, de Mercado E, Rodríguez-Martínez H. MicroRNA Expression in Specific Segments of the pig periovulatory internal genital tract is Differentially Regulated by Semen or by Seminal Plasma. Research in Veterinary Science. Available online 2 January 2024, 105134. https://doi.org/10.1016/j.rvsc.2023.105134​​